Modulated Uniaxial Compression Analysis of Respirable Pharmaceutical Powders

Compression Physics of Pharmaceutical Powders: a Review

Due to various advantages such as high-precision dosing, manufacturing efficiency and patient compliance helped making tablets the most popular dosage forms among all available dosages forms. Compaction, which is an essential manufacturing step in the manufacture of tablets, mainly includes compression (i.e. reduction of volume of the powder under consideration and particle rearrangement) and c...

Red-excitation dispersive Raman spectroscopy is a suitable technique for solid-state analysis of respirable pharmaceutical powders.

Dispersive Raman spectroscopy with excitation by a red diode laser is suitable for quantitative crystallinity measurements in powders for pulmonary drug delivery. In spray-dried mixtures of salmon calcitonin and mannitol, all three crystalline polymorphs of mannitol and amorphous mannitol were unambiguously identified and their mass fractions were measured with a limit of quantification of abou...

Compression analysis as a tool for technical characterization and classification of pharmaceutical powders

High-Sensitivity Analysis of Crystallinity in Respirable Powders Using Low Frequency Shift-Raman Spectroscopy

Analysis of uniaxial compression of vertically aligned carbon nanotubes

We carry out axisymmetric, finite deformation finite element analyses of the uniaxial compression of cylindrical bundles of vertically aligned carbon nanotubes (VACNTs) firmly attached to a Si substrate. A compressible elastic–viscoplastic constitutive relation with a piecewise, linear hardening–softening–hardening flow strength is used to model the material. Calculations are performed for VACN...